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Related Experiment Videos

CAPD disconnect systems: UK peritonitis experience.

J Lewis1, J Abbott, K Crompton

  • 1Baxter Healthcare Ltd., Compton, Berks., UK.

Advances in Peritoneal Dialysis. Conference on Peritoneal Dialysis
|January 1, 1992
PubMed
Summary

Peritonitis rates were analyzed across four UK units using two disconnect systems: Freeline (F) and Solo (S). System selection criteria influenced peritonitis incidence, with Solo showing a lower rate, especially for S. epidermidis infections.

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Area of Science:

  • Nephrology
  • Infectious Diseases
  • Medical Devices

Background:

  • Peritonitis is a significant complication in patients undergoing peritoneal dialysis.
  • Disconnect systems aim to reduce infection rates by minimizing contamination during exchanges.
  • The 'Flush Before Fill' principle is a key feature of modern disconnect systems.

Purpose of the Study:

  • To evaluate the clinical outcomes, specifically peritonitis rates and causative organisms, associated with two different disconnect systems (Freeline and Solo).
  • To compare the effectiveness of Freeline (F) and Solo (S) systems in preventing peritonitis across various clinical settings and patient populations.
  • To correlate peritonitis incidence with system selection criteria and patient characteristics.

Main Methods:

Related Experiment Videos

  • A retrospective review of peritonitis data (rates, organisms, recurrences) was conducted over 12 months in four UK dialysis units.
  • Data were analyzed based on the disconnect system used (Freeline vs. Solo), by individual unit, and in total.
  • Units employed varying criteria for system selection, including patient choice and specific population focus (e.g., blind diabetics).

    • Main Results:

    • Peritonitis incidence varied between units and systems, with specific rates detailed in the study.
    • The Solo (S) system demonstrated a potential for achieving a low incidence of peritonitis, particularly infections caused by Staphylococcus epidermidis.
    • The study suggests a relationship between patient-to-system selection criteria and the overall peritonitis rates observed.

    Conclusions:

    • Achieving a low incidence of peritonitis, especially S. epidermidis infections, is feasible with disconnect systems like Solo (S).
    • Patient and system selection criteria appear to be significant factors influencing peritonitis rates.
    • Further investigation is needed regarding the impact of recurrent peritonitis (R) and specific technical issues (ES/TI).