8-Methoxy- and p-dimethoxy-1-aminoethylhetero-tetralins: synthesis and DA, 5-HT receptors affinities
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R Perrone1, F Berardi, S Ferorelli
1Dipartimento Farmaco-Chimico, Università di Bari, Italy.
Farmaco (Societa Chimica Italiana : 1989)
|October 1, 1992
Abstract:
Two series of compounds, 8-methoxy- and p-dimethoxy derivatives of 1-aminoethylhetero-tetralins, I, were evaluated for D-2, 5-HT1 and 5-HT2 receptors affinity. No significant serotoninergic affinity was observed, whereas p-dimethoxy-derivatives 7b e 11b showed a moderate D-2 affinity.