Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Human left ventricular ultrastructure. Clinical and laboratory catheterization correlation.

A Madrazo, C A Polnitsky, V Gianelli

    Archives of Pathology & Laboratory Medicine
    |November 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Time-interval statistics applied to the analysis of low-polydispersity samples for low light-intensity levels.

    Applied optics·2010
    Same author

    Detection of subwavelength Goos-Hanchen shifts from near-field intensities: a numerical simulation.

    Optics letters·2009
    Same author

    [An analysis of the causes, characteristics, and consequences of reexposure to a drug or compound responsible for a hepatotoxicity event].

    Revista espanola de enfermedades digestivas·2008
    Same author

    Increased frequency of HLA-DR3 and complotype SC01 in Mexican Mestizo children with amebic abscess of the liver and summary of our overall HLA-SC01 experience in invasive amebiasis.

    Archives of medical research·1997
    Same author

    Esophageal motility disorders in Mexican patients with Duchenne's muscular dystrophy.

    Acta gastroenterologica Latinoamericana·1997
    Same author

    Increased frequency of HLA-DR3 and complotype SCO1 in Mexican mestizo children with amoebic abscess of the liver.

    Parasite immunology·1996

    Patients undergoing heart valve surgery showed significant left ventricular hypertrophy and ischemia. Aortic valve lesions caused more severe cardiomyopathy than mitral valve lesions, revealing unexpected degenerative changes.

    Area of Science:

    • Cardiology
    • Pathology
    • Electron Microscopy

    Background:

    • Aortic and mitral valve lesions can lead to significant cardiac remodeling.
    • Understanding the ultrastructural myocardial changes is crucial for assessing disease severity.

    Purpose of the Study:

    • To investigate ultrastructural changes in the left ventricle of patients with aortic and mitral valve lesions.
    • To compare the severity of cardiomyopathy between aortic and mitral valve lesion groups.

    Main Methods:

    • Biopsy specimens of the myocardium were obtained during surgical correction of aortic and mitral valve lesions.
    • Electron microscopy was used for ultrastructural analysis of myocardial tissue.

    Main Results:

    • Ultrastructural changes indicative of hypertrophy and ischemia were observed in the left ventricles of both patient groups.

    Related Experiment Videos

  • Cardiomyopathy severity was greater in patients with aortic valve lesions compared to those with mitral valve lesions.
  • Degenerative changes were more pronounced than anticipated based on clinical and catheterization data.

    • Conclusions:

    • Left ventricular hypertrophy and ischemia are characteristic ultrastructural findings in patients with aortic and mitral valve lesions.
    • Aortic valve lesions are associated with more severe cardiomyopathy.
    • Electron microscopy reveals significant myocardial degeneration not always evident from clinical assessments.