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[Rheumatoid arthritis. Changes in lymphocyte subsets under the effect of tiopronin]
A Lamour1, L Paolozzi, A M Leroux
1Laboratoire d'Immunologie, CHU, Brest.
Revue Du Rhumatisme Et Des Maladies Osteo-Articulaires
|September 1, 1992
Abstract:
Lymphocytes from 12 rheumatoid arthritis patients were phenotyped before and after a 2-month treatment with tiopronin. Originally reduced, CD4 CD45RA-T lymphocytes were shown to augment significantly. Abnormal activation (evaluated on HLA-DR and CD25 expression) of each cell population and sub-population was partially amended.