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Failure of nicotine to affect development of offspring when administered to pregnant rats

L M GELLER

    Science (New York, N.Y.)
    |January 23, 1959
    PubMed

    Administration of nicotine to rats at any point in pregnancy has no apparent effect upon completion or duration of pregnancy, or upon body development, litter size, weight, or mortality of offspring. These results differ sharply from the effects in mice reported by others. The possible etiologic significance of anoxia in the malformations reported in mice is discussed.

    Keywords:
    FETUS/effect of drugs onNICOTINE/effectsPREGNANCY/physiology

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