Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Loop excision for cervical intraepithelial neoplasia.

C J Tseng1, Y K Soong, C C Liang

  • 1Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Taipei, Taiwan, R.O.C.

Journal of the Formosan Medical Association = Taiwan Yi Zhi
|November 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optical design and performance of the biological small-angle X-ray scattering beamline at the Taiwan Photon Source.

Journal of synchrotron radiation·2021
Same author

Blood trace minerals concentrations and oxidative stress in patients with obstructive sleep apnea.

The journal of nutrition, health & aging·2013
Same author

NO donor KMUP-1 improves hepatic ischemia-reperfusion and hypoxic cell injury by inhibiting oxidative stress and pro-inflammatory signaling.

International journal of immunopathology and pharmacology·2013
Same author

Imaging findings in mandibular primitive neuroectodermal tumour: a report of a rare case and review of the literature.

Dento maxillo facial radiology·2011
Same author

Regulation of ovarian cancer progression by microRNA-187 through targeting Disabled homolog-2.

Oncogene·2011
Same author

Age factor and implication of human papillomavirus type-specific prevalence in women with normal cervical cytology.

Epidemiology and infection·2011

Loop electrosurgical excision procedure (LEEP) is a safe and effective treatment for cervical intraepithelial neoplasia, offering benefits like less bleeding and discomfort. This method is particularly suitable for younger women desiring future pregnancies.

Area of Science:

  • Gynecology
  • Oncology
  • Surgical Procedures

Background:

  • Cervical intraepithelial neoplasia (CIN) is a precancerous condition of the cervix.
  • Effective treatment is crucial to prevent progression to invasive cervical cancer.
  • Minimally invasive procedures are preferred for preserving reproductive health.

Purpose of the Study:

  • To compare the efficacy and safety of Loop electrosurgical excision procedure (LEEP) versus laser conization for treating cervical intraepithelial neoplasia.
  • To evaluate procedural outcomes, including operative time, blood loss, and patient discomfort.
  • To assess long-term outcomes such as recurrence rates and impact on future pregnancies.

Main Methods:

  • A prospective trial involving 97 patients with cervical intraepithelial neoplasia treated with LEEP.

Related Experiment Videos

  • A control group of 39 patients treated with laser conization.
  • Data collection included operative time, blood loss, complications, and one-year follow-up for recurrence and pregnancy outcomes.

    • Main Results:

    • LEEP demonstrated significantly shorter mean cutting and procedure times compared to laser conization (6.2s vs 11.7 min cutting time; 12.7 min vs 44.9 min total time).
    • LEEP resulted in significantly less blood loss (3.6 mL vs 11.2 mL).
    • No significant difference in recurrence rates was observed after one year; LEEP patients experienced no cervical incompetence during pregnancy.

    Conclusions:

    • LEEP is a beneficial treatment for cervical intraepithelial neoplasia, offering reduced bleeding, precise specimens, and less patient discomfort.
    • The procedure is cost-effective and suitable for younger women who may wish to have children in the future.
    • LEEP provides a safe and effective alternative to laser conization with comparable long-term oncological outcomes.