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Related Experiment Videos

Necrotising arteritis in amoebic colitis.

R B Deshpande1, M A Bharucha, J M Modhe

  • 1Dept of Pathology, PD Hinduja National Hospital, Mahim, Bombay, Maharashtra.

Journal of Postgraduate Medicine
|July 1, 1992
PubMed
Summary

Massive intestinal hemorrhage from amoebic colitis is rare. This case highlights Entamoeba histolytica causing necrotizing arteritis and severe bleeding in the cecum, necessitating surgery.

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Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Pathology

Background:

  • Amoebic colitis, caused by Entamoeba histolytica, typically presents with dysentery.
  • Massive intestinal hemorrhage is an uncommon complication of amoebic colitis.

Observation:

  • A 61-year-old diabetic male presented with massive lower intestinal hemorrhage.
  • The patient required blood transfusion and emergency surgical intervention for a caecal amoebic ulcer.

Findings:

  • Histological examination revealed Entamoeba histolytica trophozoites invading submucosal arteries.
  • Necrotizing arteritis was observed, likely leading to the rupture of a blood vessel and subsequent hemorrhage.

Implications:

  • This case underscores the potential for severe vascular complications in amoebic colitis.
  • Understanding the mechanism of arterial invasion is crucial for managing rare, life-threatening presentations of amoebiasis.

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