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[Effect of propranolol on electrophysiologic features of the heart in patients with hyperthyroidism]
T Gasińska1, F Prochaczek, M Izbicka
1I Klinika Chorób Wewnetrznych Slaskiej AM, Katowicach.
Endokrynologia Polska
|January 1, 1991
Abstract:
The effect of increasing doses of intravenously administered propranolol on electrophysiological features of heart was studied in 17 patients with untreated hyperthyroidism by using the transesophageal stimulation method. A positive and dose-dependent effect of propranolol on the studied parameters was found with the normalization of the majority of disturbances taking place after the administration of 6 mg of propranolol. This dose was safe and well tolerated by the patients. The sensitivity of the auriculo-ventricular junction to propranolol was less pronounced during the stimulated rhythm than during the sinus rhythm.