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Traveler's diarrhea: new perspectives.
1Department of Medicine, Yale University School of Medicine, New Haven, CT 06504.
Infectious Agents and Disease
|April 1, 1992
Summary
Traveler's diarrhea remains common despite advice. This review covers new approaches including antimicrobial prophylaxis, combination treatments, and a potential vaccine for infectious disease prevention in travelers.
Area of Science:
- Infectious Diseases
- Travel Medicine
- Microbiology
Background:
- Traveler's diarrhea is the most frequent infectious illness affecting international travelers, particularly to developing nations.
- Existing pre-travel advice on food and water safety is often insufficient to prevent this condition.
Purpose of the Study:
- To review emerging strategies for the prevention and treatment of traveler's diarrhea.
- To highlight advancements in antimicrobial prophylaxis, combination therapies, and vaccine development.
Main Methods:
- Literature review of recent studies and clinical trials.
- Analysis of new concepts in antimicrobial prophylaxis and treatment regimens.
- Evaluation of data on a novel potential vaccine for traveler's diarrhea.
Main Results:
- New antimicrobial prophylaxis strategies show promise in reducing incidence.
- Combination treatment with antimicrobial and antimotility agents offers an effective therapeutic approach.
- A potential vaccine is under development, representing a significant future preventive option.
Conclusions:
- Despite challenges, advancements in prophylaxis, treatment, and vaccination are improving the outlook for preventing traveler's diarrhea.
- Further research and clinical trials are essential to validate these new approaches for widespread use in travel medicine.