Dynamics of protein modifications in the skeletal muscle following formol injection

The concentrated formol injections in the skeletal muscle of rat induce the appearance of histological modifications of the destructive type, followed after a period of time by modifications of the restoring-regenerative type. The histochemical reactions for the demonstration of proteins undergo significant alterations during these processes. In a first stage the reactions are negative while during the restoration stage -- together with the appearance of myoblasts sarcoblasts and muscular buds -- they become intensely positive, as an expression of protein synthesis intensification.