Related Experiment Video
Updated: Aug 11, 2026

Surface Functionalization of Hepatitis E Virus Nanoparticles Using Chemical Conjugation Methods
Published on: May 11, 2018
Reconstituted viral envelopes--'Trojan horses' for drug delivery and gene therapy?
1Section on Membrane Structure and Function, LMMB, NCI, National Institutes of Health, Bethesda, MD 20892.
Abstract:
Reconstituted viral envelopes (RVEs) are formed by solubilizing intact virus in detergent and reassembling the envelope on removal of detergent. RVEs can be formed in the presence of agents that become encapsulated and can then be utilized in vitro and in vivo for drug delivery, cell destruction, transfer of membrane components, and as vectors for genetic engineering. The problems with biotechnological applications of RVEs and possible strategies for overcoming them are discussed in this article.
More Related Videos
Related Concept Videos
Retrovirus Life Cycles
Retroviruses
Microorganisms in Medicine and Therapeutics
Viruses with RNA Genomes
Subviral Agents
Inhibitors of Virion Maturation and Assembly

