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Updated: Jul 12, 2026
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A Convenient and General Expression Platform for the Production of Secreted Proteins from Human Cells
Published on: July 31, 2012
Production of recombinant proteins in serum-free media
D Broad1, R Boraston, M Rhodes
1Celltech Ltd., Slough, UK.
Cytotechnology
|January 1, 1991
Abstract:
The advantages of serum-free culture for the manufacture of recombinant biopharmaceuticals from mammalian cells are reviewed. The process favoured is fed-batch serum-free cell culture. This process is applicable to the majority of cell lines, is practical on the large scale, gives the lowest manufacturing cost, and can be carried out without the use of any serum.
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