Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[False decrease in pulse oximetry readings due to patent blue in a patient with breast cancer].

Tsuyoshi Murakami1, Ryotaro Kayo, Ichiro Kajita

  • 1Department of Anaesthesia, Matsushita Memorial Hospital, Moriguchi 570-8540.

Masui. the Japanese Journal of Anesthesiology
|September 19, 2003
PubMed
Summary

Patent blue dye injection during breast cancer surgery can cause a significant, temporary drop in pulse oximetry readings (SpO2). Blood gas analysis is recommended for accurate oxygen status evaluation alongside pulse oximetry when using this dye.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of the accuracy of neurologic data, survey radiographic results, or both for localization of the site of thoracolumbar intervertebral disk herniation in dogs.

American journal of veterinary research·2014
Same author

Accuracy of US-guided FNA of focal liver lesions in dogs: 140 cases (2005-2008).

Journal of the American Animal Hospital Association·2013
Same author

Analysis of clinical and ultrasonographic data by use of logistic regression models for prediction of malignant versus benign causes of ultrasonographically detected focal liver lesions in dogs.

American journal of veterinary research·2012
Same author

[Comparison of intravenous fentanyl analgesia and epidural analgesia for postoperative pain relief].

Masui. The Japanese journal of anesthesiology·2009
Same author

[Continuous intravenous administration of fentanyl reduces tenesmus after transurethral resection of the prostate (TUR-P)].

Masui. The Japanese journal of anesthesiology·2008
Same author

[Two cases of atraumatic iliopsoas hematoma].

Masui. The Japanese journal of anesthesiology·2007

Area of Science:

  • Anesthesiology
  • Surgical Oncology
  • Diagnostic Imaging

Background:

  • Sentinel lymph node biopsy is a crucial procedure in breast cancer staging.
  • Patent blue dye is commonly used for sentinel lymph node identification.
  • General anesthesia requires careful monitoring of patient oxygenation.

Observation:

  • A 61-year-old female patient undergoing breast-conserving surgery experienced a rapid SpO2 decline post-patent blue injection.
  • Pulse oximetry dropped from 100% to 60%, with subsequent recovery to 90%.
  • Arterial blood gas analysis revealed a high PaO2 (184.4 mmHg) despite low SpO2 during the event.

Findings:

  • The observed SpO2 desaturation was directly attributed to patent blue dye administration.
  • Pulse oximetry alone may not accurately reflect oxygen status during patent blue use.

Related Experiment Videos

  • Arterial blood gas analysis provided a more comprehensive assessment of oxygenation.

    • Implications:

    • Anesthesiologists and surgeons should be aware of potential SpO2 interference by patent blue.
    • Consideration of concurrent blood gas analysis is recommended for precise oxygen monitoring.
    • This finding may influence anesthetic management protocols in procedures involving patent blue dye.