Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Xeroderma pigmentosum: a case report.

Sam Park1, Murray Dock

  • 1Division of Pediatric Dentistry, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

Pediatric Dentistry
|September 19, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optimizing Daily Surgical Scheduling Improves Operative Time Consumption: A Retrospective Study.

Arthroplasty today·2026
Same author

Measuring the Bandgap of Ambipolar 2D Semiconductors using Multilayer Graphene Contact.

Small science·2025
Same author

Osseous tumors of the foot, ankle, and lower leg: a cross-sectional observational study analysing 288 cases.

The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons·2024
Same author

Soft tissue tumors of the lower leg, foot and ankle: A cross-sectional observational study analysing 376 cases.

The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons·2024
Same author

Ultrafast van der Waals diode using graphene quantum capacitance and Fermi-level depinning.

Science advances·2023
Same author

5 nm Ultrathin Crystalline Ferroelectric P(VDF-TrFE)-Brush Tuned for Hysteresis-Free Sub 60 mV dec<sup>-1</sup>  Negative-Capacitance Transistors.

Advanced materials (Deerfield Beach, Fla.)·2023
Same journal

Age-Specific Radiation Dose Distributions in Pediatric Intraoral Radiography: A Monte Carlo Analysis Across Developmental Stages.

Pediatric dentistry·2026
Same journal

Protecting Advocacy's Clout.

Pediatric dentistry·2026
Same journal

Trends in the Emergence of Permanent Dentition: A Retrospective Analysis of Adolescents From 1980 to 2020.

Pediatric dentistry·2026
Same journal

The Perceived Impact of California Sedation Legislation on Clinical Practices in Pediatric Dentistry.

Pediatric dentistry·2026
Same journal

Evaluation of Breastfeeding and Formula Feeding on Childhood Caries Experience: National Health and Nutrition Examination Survey, 2015-2018.

Pediatric dentistry·2026
Same journal

Comparative Evaluation of Compressive Strength, Microhardness, and Wear Resistance in Preformed Resin Polymer, Stainless Steel, and Zirconia Crowns.

Pediatric dentistry·2026
See all related articles

Xeroderma pigmentosum (XP) is a rare genetic disorder causing extreme UV sensitivity due to faulty DNA repair. This case study highlights essential precautions for managing XP patients, focusing on light protection and dental material selection.

Area of Science:

  • Genetics
  • Dermatology
  • Oncology

Background:

  • Xeroderma pigmentosum (XP) is a rare autosomal recessive disorder.
  • XP is characterized by defective DNA repair mechanisms, leading to extreme sensitivity to ultraviolet (UV) radiation.
  • This genetic condition significantly increases the risk of developing skin cancers.

Observation:

  • The case study focuses on a child diagnosed with xeroderma pigmentosum.
  • Clinical manifestations observed include skin and oral mucosa issues, ocular problems, and neurological impairment.
  • The study emphasizes the need for specialized care protocols for individuals with XP.

Findings:

  • Reduced activity of a specific enzyme critical for DNA repair is the underlying cause of XP.
  • Patients require stringent protective measures against UV exposure.

Related Experiment Videos

  • Careful selection of dental materials is crucial during treatment.

    • Implications:

    • This review underscores the importance of comprehensive management strategies for XP patients.
    • Implementing protective measures can mitigate disease progression and improve patient outcomes.
    • Further research into DNA repair mechanisms could lead to novel therapeutic approaches for XP and other DNA-damage-related disorders.