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New monodentate chiral phosphite ligands for asymmetric hydrogenation
Peter Hannen1, H Christian Militzer, Erasmus M Vogl
1Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, 45470 Mülheim, Germany. hannen@mpi-muelheim.mpg.de
Chemical Communications (Cambridge, England)
|September 19, 2003
Abstract:
We report the synthesis of new chiral monodentate phosphite ligands with a biphenyl backbone, the axial chirality of which is introduced early in the synthesis and locked by a chiral alkylenedioxy bridge. We also describe results obtained with these ligands in rhodium-catalysed asymmetric hydrogenation of various substrates.