Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lung transplantation. Lung preservation.

Marc de Perrot1, Shaf Keshavjee

  • 1Toronto Lung Transplant Program, Toronto General Hospital, University Health Network, University of Toronto, 200 Elizabeth Street, EN 10-224, Toronto, Ontario M5G 2C4, Canada.

Chest Surgery Clinics of North America
|September 19, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of intraoperative specimen computed tomography imaging on grossing accuracy and margin assessment in pulmonary wedge resection.

JTCVS open·2026
Same author

Preoperative circulating tumor DNA detection and occult lymph node metastases in clinical stage I lung cancer: The lung DETECT study.

JTCVS open·2026
Same author

Ten-year review of endobronchial ultrasound-guided transbronchial needle aspiration for lymph node staging in lung cancer: Comparison with guidelines.

JTCVS open·2026
Same author

Update on Pleural Epithelioid Mesothelioma: New Insights for Diagnosis and Patient Management.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer·2026
Same author

Pulmonary Artery Sarcoma Study: A Multi-Centre European Society of Thoracic Surgeons Working Group Evaluating Diagnosis, Treatment, and Outcomes.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2026
Same author

Distinct endothelial cells in chronic thromboembolic pulmonary hypertension.

NPJ cardiovascular health·2026
Same journal

New treatment modalities for end-stage emphysema.

Chest surgery clinics of North America·2003
Same journal

Cost effectiveness of lung volume reduction surgery.

Chest surgery clinics of North America·2003
Same journal

Results of lung volume reduction surgery for emphysema.

Chest surgery clinics of North America·2003
Same journal

Complications after lung volume reduction surgery.

Chest surgery clinics of North America·2003
Same journal

Operative techniques for lung volume reduction surgery.

Chest surgery clinics of North America·2003
Same journal

Patient selection for lung volume reduction surgery.

Chest surgery clinics of North America·2003
See all related articles

Improving donor lung utilization is critical for lung transplantation. New strategies to assess and repair lungs, alongside understanding preservation mechanisms, can increase transplant numbers and graft survival.

Area of Science:

  • Transplantation immunology
  • Organ preservation science

Background:

  • Lung transplantation outcomes have improved due to better preservation techniques, reducing ischemia-reperfusion injury.
  • A significant challenge persists in increasing the availability of donor lungs, with only 10-30% currently utilized.

Purpose of the Study:

  • To highlight the need for strategies to improve donor lung quality and availability.
  • To explore the link between acute lung injury and chronic graft dysfunction.
  • To identify potential therapeutic targets for enhanced lung preservation.

Main Methods:

  • Review of advancements in lung preservation techniques.
  • Discussion of current limitations in donor lung utilization.
  • Exploration of future research directions, including genetic analysis and microarray technologies.

Related Experiment Videos

Main Results:

  • Improvements in lung preservation have reduced acute lung injury post-transplantation.
  • Low donor lung utilization rates necessitate innovative solutions.
  • Understanding injury mechanisms can guide new therapeutic development.

Conclusions:

  • Developing methods to assess, repair, and improve donor lung quality is crucial for increasing transplant numbers.
  • Further research into lung preservation mechanisms may reveal links to chronic graft dysfunction.
  • Genetic analysis holds promise for identifying novel therapeutic targets to enhance lung preservation and transplant success.