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Updated: Aug 6, 2026
Assessing Bacterial Invasion of Cardiac Cells in Culture and Heart Colonization in Infected Mice Using Listeria monocytogenes
Published on: May 27, 2015
A preliminary investigation into light-modulated replication of nanobacteria and heart disease
Andrei P Sommer1, Uri Oron, Anne-Marié Pretorius
1Central Institute of Biomedical Engineering, University of Ulm, 89081 Ulm, Germany. samoan@gmx.net
Objective:
The purpose of this preliminary study is to evaluate the effect of various wavelengths of light on nanobacteria (NB).
Background Data:
NB and mitochondria use light for biological processes. NB have been described as multifunctional primordial nanovesicles with the potential to utilize solar energy for replication. NB produce slime, a process common to living bacteria. Slime release is an evolutionary important stress-dependent phenomenon increasing the survival chance of individual bacteria in a colony. In the cardiovascular system, stress-induced bacterial colony formation may lead to a deposition of plaque.
Methods:
Cultured NB were irradiated with NASA-LEDs at different wavelengths of light: 670, 728 and 880 nm. Light intensities were about 500k Wm(-2), and energy density was 1 x 10(4) J m(-2).
Results:
Monochromatic light clearly affected replication of NB. Maximum replication was achieved at 670 nm.
Conclusions:
The results indicate that suitable wavelengths of light could be instrumental in elevating the vitality level of NB, preventing the production of NB-mediated slime, and simultaneously increasing the vitality level of mitochondria. The finding could stimulate the design of cooperative therapy concepts that could reduce death caused by myocardial infarcts.
