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Hallucinogens: an update.

John H Halpern¹

¹Biological Psychiatry Laboratory, Alcohol and Drug Abuse Research Center, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA. john_halpern@hms.harvard.edu

Current Psychiatry Reports

|September 19, 2003

Summary

This review explores less common hallucinogens like Salvia divinorum and ecstasy, examining their therapeutic potential and religious use. It offers clinical insights into hallucinogen persisting perception disorder and potential anti-addiction applications.

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Area of Science:

Psychiatry
Pharmacology
Neuroscience

Background:

Limited research exists on the therapeutic and religious uses of hallucinogens.
Existing research primarily focuses on epidemiology and pathology of hallucinogen abuse.

Observation:

This paper reviews less common hallucinogens (e.g., Salvia divinorum, ecstasy, synthetic analogs) and hallucinogen persisting perception disorder.
Case vignettes suggest potential anti-addictive properties of hallucinogens.
The religious and sacramental use of hallucinogens is examined.

Findings:

Hallucinogens are physiologically nonaddictive and may offer legitimate benefits.
Hallucinogen persisting perception disorder is rare but reviewed with treatment recommendations.
Clinical research status and potential therapeutic applications are presented.

Implications:

Clinicians can gain a nuanced understanding of hallucinogen benefits and risks.
This information can better equip clinicians to discuss hallucinogen use and abuse with patients.
Further methodologically sound research may validate therapeutic applications of hallucinogens.

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