Related Experiment Video
Updated: Sep 13, 2026

Intravascular Perfusion of Carbon Black Ink Allows Reliable Visualization of Cerebral Vessels
Published on: January 4, 2013
Bilateral cerebrovascular accidents in incontinentia pigmenti
Loretta Fiorillo1, D Barry Sinclair, Mary L O'Byrne
1Division of Pediatric Dermatology, Walter Mackenzie health Sciences Centre, University of Alberta, Edmonton, Alberta, Canada.
Abstract:
Incontinentia Pigmenti is an X-linked dominant neurocutaneous disorder with central nervous system manifestations in 30% of cases, including seizures and mental retardation. Ischemic or hemorrhagic cerebrovascular accidents have been reported rarely in incontinentia pigmenti. Chart review and literature search was performed following identification of the index case. We describe a patient with incontinentia pigmenti who developed bilateral cerebrovascular accidents in the neonatal period, with resultant severe neurologic sequelae. This is the second reported case of bilateral cerebrovascular accidents in a patient with incontinentia pigmenti. This finding may be secondary to cerebrovascular anomalies, similar to those observed in the retina. Recognition of cerebrovascular accidents as a complication of incontinentia pigmenti will hopefully lead to earlier recognition and treatment.
Related Concept Videos
Cerebral Edema ll: Pathophysiology
Hemorrhagic Stroke ll: Pathophysiology
Hemorrhagic Stroke l: Introduction
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Ischemic Stroke ll: Pathophysiology
Diabetic Retinopathy
