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Updated: Sep 13, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
Antioxidant activity of thioureidic derivatives I
Carmela Saturnino1, Marta D'Auria, Nicola Paesano
1Department of Pharmaceuticals Sciences, University of Salerno, Via Ponte Don Melillo, 84084 Fisciano (SA), Italy. saturnino@unisa.it
Abstract:
Recent developments in biomedical science have shown that free radicals are involved in many diseases. They attack the unsaturated fatty acids in the biomembrane resulting in membrane lipid peroxidation, which is strongly connected to aging, carcinogenesis and atherosclerosis. Free radicals also attack DNA and cause mutation leading to cancer. In addition lipid peroxidation is an important factor of deterioration in the processing and storage of food. Therefore, it is important to search for new effective radical scavengers (Sci. Rev. 2 (1997) 152; J. Nat. Prod. Rev. 63 (2000) 1035). In this manuscript we describe the antioxidant activity of new thioureidic compounds.
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