Related Experiment Videos
Globin gene switching: a paradigm or what?
1Leukemia Research Fund Centre, Chester Beatty Laboratories, London, UK.
Current Opinion in Biotechnology
|December 1, 1991
Abstract:
The delineation of the beta-globin locus control region has led to a new understanding of the developmental regulation of the beta-globin gene cluster. It now seems that globin gene switching is effected through the sequential and mutually exclusive interaction of the locus control region with the embryonic, fetal and adult stage specific globin genes.