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Laser immunotherapy: a novel treatment modality for metastatic tumors
Wei R Chen1, Raoul Carubelli, Hong Liu
1Biomedical Engineering Program, Department of Physics and Engineering, University of Central Oklahoma, 100 N. University Drive, Edmond, OK 73034, USA. wchen@ucok.edu
Molecular Biotechnology
|September 19, 2003
Abstract:
Laser immunotherapy is a novel approach for the treatment of metastatic tumors. It combines a selective photothermal laser-tissue interaction for direct tumor destruction and an immunoadjuvant-directed simulation for immune responses. In experiments using a rat metastatic tumor model, laser immunotherapy resulted in the eradication of both treated primary tumors and untreated metastases at remote sites. It also induced anti-tumor resistance.