Modulation of Thrombophilia Genes by Environmental Factors

Immunogenic implications of translational readthrough modulate the association of F8 nonsense mutations with inhibitors in Hemophilia A.

Molecular medicine (Cambridge, Mass.)·2026

Rational design of a novel engineered factor X with chimeric activation peptide as bypassing agent for hemophilia.

Journal of thrombosis and haemostasis : JTH·2026

Tailored collagen binding of albumin-fused hyperactive coagulation factor IX dictates in vivo distribution and functional properties.

Nature communications·2025

Genetic determinants of activated factor VII-antithrombin plasma levels and mortality in patients with coronary artery disease.

Thrombosis research·2025

Selected cell receptor genotypes differentially modulate the ABO blood group influence on Factor VIII levels in severe aortic stenosis.

Thrombosis research·2025

Pharmacokinetics of Efmoroctocog alfa by Two-Compartment Model Highlights Hemophilia A Patients with Biphasic Decay, Long Mean Residence Time, and Beta Half-Life.

Journal of clinical medicine·2024

Splenomegaly in primary antiphospholipid syndrome without accompanying portal hypertension or comorbidity.

Pathophysiology of haemostasis and thrombosis·2011

The influence of tissue factor and tissue factor pathway inhibitor polymorphisms on thrombin generation in stable coronary artery disease.

Pathophysiology of haemostasis and thrombosis·2011

Impact of chemotherapy on thrombin generation and on the protein C pathway in breast cancer patients.

Pathophysiology of haemostasis and thrombosis·2011

The effect of chronic cadmium toxicity on blood pressure and plasma viscosity.

Pathophysiology of haemostasis and thrombosis·2011

Serum and saliva sialic acid in periodontitis patients with and without cardiovascular disease.

Pathophysiology of haemostasis and thrombosis·2011

Plasma tissue factor levels and salivary tissue factor activities of periodontitis patients with and without cardiovascular disease.

Pathophysiology of haemostasis and thrombosis·2011

Correction: Shared and condition-associated gut microbiota alterations in older adults with depression and constipation: evidence from the American Gut Project.

Frontiers in microbiology·2026

Clinically altered brain activity may not look like aged brain activity: Implications for brain-age modeling and biomarker strategies.

Alzheimer's & dementia (New York, N. Y.)·2026

Research progress and application prospects of multi-omics integration strategies in precision risk stratification of type 1 diabetes mellitus.

Frontiers in immunology·2026

Investigating the causal impact of gut microbiota on periodontitis based on Mendelian randomization, bulk transcriptomics, and single-cell transcriptomics.

Frontiers in cell and developmental biology·2026

Partitioned blood pressure polygenic risk reveals differential genetic effects of tissue-specific enhancers and their interactions on cardiovascular disease.

Research square·2026

Enhanced chromatin compaction is associated with de novo expression of a nuclear microprotein, global loss of H3 acetylation and local transcriptional changes in retinal rod photoreceptors.

Research square·2026

Related Experiment Videos

Modulation of Thrombophilia Genes by Environmental Factors

Related Concept Videos

Immunogenic implications of translational readthrough modulate the association of F8 nonsense mutations with inhibitors in Hemophilia A.

Rational design of a novel engineered factor X with chimeric activation peptide as bypassing agent for hemophilia.

Tailored collagen binding of albumin-fused hyperactive coagulation factor IX dictates in vivo distribution and functional properties.

Genetic determinants of activated factor VII-antithrombin plasma levels and mortality in patients with coronary artery disease.

Selected cell receptor genotypes differentially modulate the ABO blood group influence on Factor VIII levels in severe aortic stenosis.

Pharmacokinetics of Efmoroctocog alfa by Two-Compartment Model Highlights Hemophilia A Patients with Biphasic Decay, Long Mean Residence Time, and Beta Half-Life.

Splenomegaly in primary antiphospholipid syndrome without accompanying portal hypertension or comorbidity.

The influence of tissue factor and tissue factor pathway inhibitor polymorphisms on thrombin generation in stable coronary artery disease.

Impact of chemotherapy on thrombin generation and on the protein C pathway in breast cancer patients.

The effect of chronic cadmium toxicity on blood pressure and plasma viscosity.

Serum and saliva sialic acid in periodontitis patients with and without cardiovascular disease.

Plasma tissue factor levels and salivary tissue factor activities of periodontitis patients with and without cardiovascular disease.

Correction: Shared and condition-associated gut microbiota alterations in older adults with depression and constipation: evidence from the American Gut Project.

Clinically altered brain activity may not look like aged brain activity: Implications for brain-age modeling and biomarker strategies.

Research progress and application prospects of multi-omics integration strategies in precision risk stratification of type 1 diabetes mellitus.

Investigating the causal impact of gut microbiota on periodontitis based on Mendelian randomization, bulk transcriptomics, and single-cell transcriptomics.

Partitioned blood pressure polygenic risk reveals differential genetic effects of tissue-specific enhancers and their interactions on cardiovascular disease.

Enhanced chromatin compaction is associated with de novo expression of a nuclear microprotein, global loss of H3 acetylation and local transcriptional changes in retinal rod photoreceptors.

Related Experiment Videos

Modulation of Thrombophilia Genes by Environmental Factors

Related Concept Videos

Related Articles