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Updated: Jun 20, 2026

Measuring DNA Damage and Repair in Mouse Splenocytes After Chronic In Vivo Exposure to Very Low Doses of Beta- and Gamma-Radiation
Published on: July 4, 2015
Gamma-radiation dose-rate effects on DNA damage and toxicity in bacterial cells
Jiho Min1, Chang Woo Lee, Man Bock Gu
1National Research Laboratory of Environmental Biotechnology, Kwangju Institute of Science and Technology, 1 Oryong-dong Buk-gu, 500-712 Gwangju, Republic of Korea.
Abstract:
In order to investigate the relationship between radiation dose-rate and bacterial DNA damage as well as general cellular toxicity, two recombinant Escherichia coli strains, DPD2794 and GC2 were used. Following gamma-ray irradiation, these bioluminescent bacteria showed quantitative stress responses in terms of DNA damage and general toxicity depending on the dose rates of energy deposition, i.e. dose-rate of radiation. In addition, an inverse relationship was found, at lower dose rates between 0.5 and 1 Gy/h and a parabolic relationship at dose rates between 0.5 and 2.6 Gy/h.
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