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A bidesmosidic oleanolic acid saponin from Panax pseudo-ginseng.
Y N Shukla1, R S Thakur, P Pachaly
1Central Institute of Medicinal and Aromatic Plants, Lucknow, India.
Phytochemistry
|March 1, 1992
Summary
Researchers identified a new compound, pseudo-ginsenoside-RI3, from Panax pseudo-ginseng rhizomes. This novel triterpenoid saponin was fully characterized using various physicochemical methods.
Area of Science:
- Natural Product Chemistry
- Phytochemistry
- Pharmacognosy
Background:
- Panax pseudo-ginseng subsp. himalaicus var. angustifolius is a plant source of bioactive compounds.
- Triterpenoid saponins are a class of natural products with diverse biological activities.
Purpose of the Study:
- To isolate and characterize a novel triterpenoid saponin from Panax pseudo-ginseng rhizomes.
- To elucidate the chemical structure of the newly discovered compound.
Main Methods:
- Isolation of the compound from plant extracts.
- Physicochemical methods including spectroscopic analyses for structural elucidation.
Main Results:
- A novel triterpenoid saponin, named pseudo-ginsenoside-RI3, was successfully isolated.
- The structure was determined to be 3-O-beta-D-glucopyranosyl(1----2)-beta-D-glucuronopyranosyl (1----6)-beta-D-glucopyranosyl 28-O-beta-D-xylopyranosyl-olean-12-en-28-oic acid ester.
Conclusions:
- The characterization of pseudo-ginsenoside-RI3 expands the known repertoire of saponins from this plant species.
- This finding contributes to the understanding of the chemical diversity within the Panax genus.