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Binding of low molecular mass compounds to proteins studied by liquid chromatographic techniques
Tibor Cserháti1, Esther Forgács, Zdenek Deyl
1Institute of Chemistry, Chemical Research Center, Hungarian Academy of Sciences, PO Box 17, 1525 Budapest, Hungary.
Biomedical Chromatography : BMC
|September 19, 2003
Abstract:
The newest achievements in the application of miscellaneous liquid chromatographic techniques such as size-exclusion, ion-exchange and reversed-phase high-performance liquid chromatography, and thin-layer chromatography for the elucidation of the various aspects of the binding of ligands to proteins are compiled and briefly discussed. Examples of employment in pharmaceutical and clinical chemistry, drug design, enzyme kinetic studies and environmental protection are presented.