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The Use of a β-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions
Published on: February 1, 2018
Biosensors for process monitoring
1Institut für Technische Chemie, Hannover, F.R.G.
Biosensor research in Germany focuses on bioprocess monitoring using in situ sensors and flow injection analysis. Technologies like enzyme thermistors and field-effect transistors enable real-time process control.
Area of Science:
- Biotechnology
- Analytical Chemistry
- Process Engineering
Background:
- Post-reunification biosensor research in the Federal Republic of Germany (F.R.G.) is reviewed.
- Biosensor principles are fundamental to modern bioprocess monitoring.
Purpose of the Study:
- To provide an overview of biosensor research activities in the F.R.G. post-reunification.
- To present the principles and applications of biosensors for bioprocess monitoring.
Main Methods:
- Review of in situ sensor technologies.
- Analysis of biosensors based on flow injection analysis (FIA).
- Examination of specific biosensor applications.
Main Results:
- Discussion of a four-channel enzyme thermistor for process monitoring.
- Exploration of bio-field effect transistors (BioFETs) in bioprocesses.
- Presentation of immunoanalysis systems for real-time monitoring.
Conclusions:
- Biosensors offer significant potential for effective bioprocess monitoring.
- Various advanced biosensor technologies are being developed and applied in Germany.
- Continued research is crucial for optimizing biosensor applications in industrial bioprocesses.
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