Related Experiment Videos
On-line assessment of metabolic activities based on culture redox potential and dissolved oxygen profiles during
1Chemical and Biochemical Engineering Program, University of Maryland, Baltimore 21228.
Biotechnology Progress
|November 1, 1992
Abstract:
We report here on the utility of on-line culture redox potential and dissolved oxygen measurements to identify metabolic changes in fermentation by Corynebacterium glutamicum under aerobic conditions. Metabolic changes were identified by observing discrepancies in the profile of culture redox potential and dissolved oxygen. On the basis of these measurements, we can identify the end of the lag phase, threonine exhaustion, and glucose exhaustion during fermentation.