[Ocular localizations of disseminated candidiasis]

Area of Science:

• Ophthalmology
• Mycology
• Infectious Diseases

Background:

• The incidence of disseminated Candida infections has significantly increased over the past five years.
• Ocular candidiasis, specifically involving the choroid and retina, represents a serious manifestation of systemic fungal spread.

Purpose of the Study:

• To present a series of 9 cases of disseminated Candida infections localized to the choroid and retina.
• To review the existing literature on this condition.
• To discuss predisposing factors, diagnostic features, and prognostic indicators.

Main Methods:

• Case series presentation.
• Literature review focusing on disseminated candidiasis and ocular involvement.
• Analysis of clinical data from 9 patients with choroidoretinal Candida infections.

Main Results:

• Nine cases of disseminated Candida infections affecting the choroid and retina were identified.
• Key predisposing factors identified include poor general health, antibiotic therapy, compromised immune defenses, and surgical interventions (abdominal/cardiovascular).
• Discussion of local and systemic diagnostic and prognostic signs relevant to these infections.

Conclusions:

• Disseminated Candida infections, including those affecting the choroid and retina, are an increasing concern.
• Recognizing risk factors and understanding diagnostic and prognostic features are crucial for managing these challenging infections.