Related Experiment Video
Updated: Sep 3, 2026
Isolation of Double Negative αβ T Cells from the Kidney
Published on: May 16, 2014
T lymphocyte subsets in chronic uremic patients treated with maintenance hemodialysis
L Morra1, G A Ponassi, G Gurreri
1Istituto Scientifico di Medicina Interna (ISMI), University of Genoa, Italy.
Abstract:
Blood T lymphocyte subsets have been studied using monoclonal antibodies in 10 chronic uremic patients treated with maintenance hemodialysis. Both total T lymphocytes identified by the antibody OKT3, and the helper-inducer T lymphocyte subset identified by the antibody OKT4 were found to be significantly lower than normal. The cytotoxic-suppressor T cell subset was only moderately, even if significantly reduced, so that the T4/T8 ratio in uremic patients was significantly lower than normal. These data provide an additional contribution to the interpretation of immunological and hematological deficiencies observed in chronic uremia.
More Related Videos
09:20Intracellular Staining and Flow Cytometry to Identify Lymphocyte Subsets within Murine Aorta, Kidney and Lymph Nodes in a Model of Hypertension
Published on: January 28, 2017
11:39Subcellular Fractionation of Primary Chronic Lymphocytic Leukemia Cells to Monitor Nuclear/Cytoplasmic Protein Trafficking
Published on: October 23, 2019
Related Concept Videos
01:19Multipotency of Hematopoietic Stem Cells
01:27Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...