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Aneuploidy in nonneoplastic and benign melanocytic and breast lesions determined by DNA flow cytometry

J V Frei1, V J Martinez

  • 1Department of Pathology, University of Western Ontario, London, Canada.

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc
|November 1, 1992
PubMed

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Flow Cytometry01:23

Flow Cytometry

The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
In...