Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Endoprosthetic replacement for bony metastases.

D Chan1, S R Carter, R J Grimer

  • 1Bone Tumour Treatment Service, Royal Orthopaedic Hospital, Birmingham.

Annals of the Royal College of Surgeons of England
|January 1, 1992
PubMed
Summary

Endoprosthetic replacement effectively treats long bone metastases, restoring mobility and pain relief in patients. This palliative procedure offers improved quality of life for selected individuals with bone cancer spread.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genetic diagnosis for osteogenesis imperfecta: abridged secondary publication.

Hong Kong medical journal = Xianggang yi xue za zhi·2025
Same author

A whole genomic CRISPR-Cas9 screen identifies the amino acid transporter <i>SLC43A1</i> (LAT3) as a major determinant of oxaliplatin sensitivity in colorectal cancer cells.

bioRxiv : the preprint server for biology·2025
Same author

Oral Food Challenges for Food Protein-Induced Enterocolitis Syndrome-A 10-Year Multicentre Audit.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2025
Same author

Lipidomic Analysis Reveals Drug-Induced Lipoxins in Glaucoma Treatment.

bioRxiv : the preprint server for biology·2025
Same author

A clinico-radiological review of chronic non-bacterial osteomyelitis in paediatrics, adolescents, and adults: demystifying a forgotten differential.

Clinical radiology·2023
Same author

Maternal congenital diaphragmatic hernia which first presented in second pregnancy.

European journal of obstetrics & gynecology and reproductive biology: X·2023

Area of Science:

  • Orthopedic Surgery
  • Oncology
  • Medical Engineering

Background:

  • Long bone metastases often cause pathological fractures, significantly impacting patient mobility and quality of life.
  • Surgical intervention is frequently required to manage destructive bone lesions resulting from metastatic cancer.
  • Endoprosthetic reconstruction offers a potential solution for bone defects caused by metastases.

Purpose of the Study:

  • To review the outcomes of endoprosthetic replacement in patients with long bone metastases.
  • To evaluate the efficacy, complications, and survival rates associated with this surgical technique.
  • To define the indications for endoprosthetic replacement in the palliative treatment of bone metastases.

Main Methods:

  • Retrospective review of 38 patients treated with resection of metastatic lesions and endoprosthetic replacement.

Related Experiment Videos

  • Analysis of patient mobility, pain status, survival rates, and complications.
  • Categorization of primary tumor types and metastasis characteristics.

    • Main Results:

    • All 38 patients achieved independent mobility and were pain-free post-surgery.
    • The average survival rate following endoprosthetic replacement was 14.7 months, varying by primary tumor.
    • Common primary sources included hypernephroma and breast carcinoma; most patients had solitary metastases.

    Conclusions:

    • Endoprosthetic replacement is an effective palliative procedure for selected patients with long bone metastases.
    • The technique successfully restores function and alleviates pain, improving quality of life.
    • Careful patient selection is crucial for optimal outcomes in managing metastatic bone disease.