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Related Experiment Videos

Neural elements in human cervical intervertebral discs.

T Mendel1, C S Wink, M L Zimny

  • 1Department of Anatomy, Louisiana State University Medical Center, New Orleans.

Spine
|February 1, 1992
PubMed
Summary
This summary is machine-generated.

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Human cervical intervertebral discs contain nerve fibers and mechanoreceptors. These neural elements, including Pacinian corpuscles and Golgi tendon organs, are found throughout the disc, particularly in the posterolateral regions.

Area of Science:

  • Neuroscience
  • Anatomy
  • Histology

Background:

  • The innervation of the human cervical intervertebral disc is not fully understood.
  • Previous research suggests the presence of neural elements, but detailed characterization is lacking.

Purpose of the Study:

  • To characterize the neural elements within the human cervical intervertebral disc.
  • To identify the types and distribution of nerve fibers and mechanoreceptors.

Main Methods:

  • Human cervical intervertebral discs were obtained from four adult autopsy specimens.
  • Discs were processed using bulk gold chloride staining.
  • Sections were examined using light microscopy.

Main Results:

Related Experiment Videos

  • Nerve fibers were observed entering the disc from the posterolateral aspect.
  • Nerves were present throughout the anulus fibrosus, with higher concentrations in the middle third.
  • Mechanoreceptors, including structures resembling Pacinian corpuscles and Golgi tendon organs, were identified in the upper third, posterolateral region.
  • Conclusions:

    • The human cervical intervertebral disc is innervated by nerve fibers.
    • The disc contains various mechanoreceptors, suggesting a role in sensory feedback.
    • These findings contribute to understanding the neuroanatomy of the cervical spine.