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Cigarette smoking, obesity, and benign prostatic hypertrophy: a prospective population-based study
W R Seitter1, E Barrett-Connor
1Department of Community and Family Medicine, University of California, San Diego, La Jolla 92093-0607.
American Journal of Epidemiology
|March 1, 1992
Summary
This study found no significant link between smoking or obesity and the development of surgically treated benign prostatic hypertrophy (BPH) in men. Further research is needed to understand BPH risk factors.
Area of Science:
- Urology
- Epidemiology
- Public Health
Background:
- Benign prostatic hypertrophy (BPH) is a common condition affecting aging men, often requiring surgical intervention.
- Lifestyle factors such as smoking and obesity are frequently investigated for their potential role in BPH development.
Purpose of the Study:
- To investigate the association between smoking status and obesity and the risk of surgically treated benign prostatic hypertrophy.
Main Methods:
- A prospective study of 929 white men aged 40-79, followed for an average of 12 years.
- Data on smoking habits and body mass index (BMI) were collected and analyzed.
- Relative risks were calculated using age-adjusted and multivariate analyses.
Main Results:
- No statistically significant increased risk of BPH was observed in current or former smokers compared to nonsmokers (RR=1.1).
- Obesity (BMI > 26.75) was not associated with an increased risk of BPH (RR=0.9).
- Multivariate analysis confirmed no significant relationship between smoking, obesity, and surgically treated BPH.
Conclusions:
- The study did not find evidence to support a link between cigarette smoking or obesity and the development of surgically treated benign prostatic hypertrophy.
- These lifestyle factors may not be significant predictors for the need for BPH surgery.