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Updated: Jul 19, 2026
08:00
Generation of Human Nasal Epithelial Cell Spheroids for Individualized Cystic Fibrosis Transmembrane Conductance Regulator Study
Published on: April 11, 2018
Summary
Over 98% of cystic fibrosis mutations are detectable in Brittany
Area of Science:
- Medical Genetics
- Population Health
Background:
- Cystic Fibrosis (CF) is a genetic disorder.
- Genetic mutations are the cause of CF.
- Specific populations may have unique mutation profiles.
Purpose of the Study:
- To assess the feasibility of carrier screening for cystic fibrosis.
- To evaluate the prevalence of cystic fibrosis mutations in Brittany, France.
Main Methods:
- Genetic analysis of a Celtic population in Brittany.
- Mutation detection for cystic fibrosis.
Main Results:
- Over 98% of cystic fibrosis mutations were identified in the Brittany population.
- High detection rate suggests potential for carrier screening.
Conclusions:
- Carrier screening for cystic fibrosis is highly feasible in Brittany.
- Genetic screening programs could be implemented effectively in this population.
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