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Cardiac myxoma with a cytokeratin-immunoreactive glandular component
1Department of Pathology, University Medical Center, Geneva, Switzerland.
Pathology, Research and Practice
|February 1, 1992
Abstract:
This study documents the expression of cytokeratin intermediate filaments (IFs) in a surgically excised glandular atrial myxoma. The glandular structures showed also positivity for carcinoembryonic antigen. Typical isolated or cordlike myxoma cells contained vimentin IFs. Positivity for von Willebrand factor was detected in cells lining deep invaginations of surface papillae and vascular channels. Bundles of smooth muscle cells and myofibroblasts scattered throughout the myxoid matrix synthesized the isoform of alpha-actin specific for smooth muscle.