[New possibilities in the treatment of panniculosis using hyaluronidase]

364 patients were examined for changes of cutaneous and subcutaneous adipose tissue, as they appear in idiopathic panniculosis. There was not found a fundamental difference between the generalized and by far more frequently appearing partial changes of the skin, the consecutive panniculitis. The transition between the two forms is flowing. In contrast to the simple placebo test 25 patients, among them 12 cases with idiopathic panniculosis, could for the most part be treated successfully by highly dosed intravenous applications of hyaluronic acid. There was not established a connection between the decrease of the cutaneous changes and the reduction of the secretion of the mycopolysaccharides in the urine.