A VEP study of the visual pathway function in compressive lesions of the optic chiasm. Full-field versus half-field...

Changes of the pattern reversal visual evoked potentials (VEPs) to half- and full-field stimulation in 50 patients with compressive lesions of the optic chiasm are presented. Temporal half-field stimulation yielded abnormal responses in 85% of the eyes, showing non-recordable P100 in 50% of eyes, while in 35% the P100 was significantly attenuated or delayed. With nasal half-field the percentage of all detectable abnormalities was lower (36% of the eyes). Full-field stimulation revealed VEP abnormalities in 74% of eyes and therefore proved less sensitive than the half-field stimulation. This study adds new evidence that half-field stimulation can be an important adjunct for assessing the function of the optic chiasm.