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[Acute lethal alcohol intoxication (author's transl)].

B Kringsholm

    Zeitschrift Fur Rechtsmedizin. Journal of Legal Medicine
    |January 1, 1976
    PubMed
    Summary

    Acute alcohol intoxication can cause death, with cardiac hypertrophy more common at lower blood alcohol levels. This suggests alcohol

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    Area of Science:

    • Forensic Pathology
    • Toxicology
    • Cardiology

    Context:

    • Examined 92 autopsy cases of suspected acute alcohol intoxication over 18 years.
    • Included individuals with chronic alcohol abuse and varying blood alcohol concentrations (2.04–4.92 o/oo).

    Purpose:

    • Investigate the relationship between blood alcohol levels, pre-existing conditions, and cause of death.
    • Explore the mechanism of death in acute alcohol intoxication, particularly concerning cardiac involvement.

    Summary:

    • Fatty liver and cirrhosis were equally frequent in low and high blood alcohol groups.
    • Cardiac hypertrophy was significantly more prevalent in the low lethal blood alcohol group.
    • Death timing (absorption vs. elimination phase) differed between those with and without cardiac hypertrophy.

    Impact:

    • Highlights the complex interplay between alcohol concentration, cardiac status, and mortality.
    • Suggests cardiac hypertrophy may influence the mechanism and timing of death in alcohol intoxication.
    • Underscores the need for careful interpretation of post-mortem alcohol levels and associated pathologies.

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