[Foundations of modern chemotherapy of malignant tumors]

Position of tumour chemotherapy among tumour treatment. Cytostatics as a systemic active means of tumour management. Adjuvant application of chemotherapy in the postoperative period. Achievements of nowadays chemotherapy in some tumours. Rules of chemotherapy action on tumours, tumour biological considerations. Cytokinetic aspects of tumour chemotherapy. Critics on partial synchronization. Specialties of the chemotherapy in the field of head and neck tumours. Some dosage recommendations for a few drugs to be systematically or locally administered. Possibilities for potentiating of cytostatic action--by using the oncobiogram, anticoagulation or defibrination and immunostimulation, respectively. Clinical evaluation of cytostatic effectivity applying the method of randomized clinically controlled study.