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A 35 kDa Fos-related antigen is co-localized with substance P and dynorphin in striatal neurons
W Q Zhang1, K R Pennypacker, H Ye
1Laboratory of Molecular and Integrative Neuroscience, National Institute of Environmental Health Sciences, National Institute of Health Research Triangle Park, NC 27709.
Brain Research
|April 17, 1992
Abstract:
The rat striatum after dopamine denervation followed by repeated apomorphine treatment was examined for the co-expression of c-fos and Fos-related antigens with dynorphin, substance P and [Met5]enkephalin using Western blot and immunohistochemical techniques. Administration of apomorphine, a dopamine agonist, elevated the level of 35 kDa Fos-related antigen which co-localized with dynorphin and substance P, but not enkephalin, in striatal neurons.