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Banked blood microfiltration. II. Dacron-wool microfilter.

R G Guidoin, T Gilchrist

    British Journal of Haematology
    |August 1, 1976
    PubMed
    Summary
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    Blood storage causes debris accumulation, potentially leading to lung microemboli. Microfiltration using the Swank IL200 filter effectively removes over 70% of debris, with lactate priming enhancing efficiency.

    Area of Science:

    • Transfusion Medicine
    • Biomaterials Science

    Background:

    • Accumulation of particulate debris in banked blood increases with storage duration.
    • Transfusion of stored blood can lead to pulmonary microembolism due to filtered debris in the lung capillaries.

    Purpose of the Study:

    • To evaluate the efficacy of the Swank IL200 transfusion filter for removing particulate debris from banked blood.
    • To assess the impact of lactate priming on the debris removal efficiency of the filter.

    Main Methods:

    • Utilized the Swank IL200 filter, composed of Dacron wool, for microfiltration of banked blood units.
    • Quantified debris removal efficiency for particles in the 29-100 micrometer size range.
    • Investigated the effect of lactate priming on filter performance.

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    Main Results:

    • The Swank IL200 filter removed over 70% of debris (29-100 µm) from four units of banked blood.
    • Lactate priming significantly enhanced the particle removal efficiency of the filter.

    Conclusions:

    • Microfiltration with the Swank IL200 filter is an effective method to prevent microemboli caused by blood debris.
    • Lactate priming offers a strategy to improve the performance of transfusion filters for banked blood.