Related Experiment Video
Updated: Aug 10, 2026

07:45
Severe Burn Injury in a Swine Model for Clinical Dressing Assessment
Published on: November 6, 2018
[Efficacy of the use of a stabilized alpha2-macroglobulin concentrate in experimental burns]
Abstract:
The effectiveness of the use of a stabilized composition of alpha 2-macroglobulin concentrate obtained from fraction III of plasma proteins according to Cohn in burn disease in the experiment on guinea pigs was studied. Under the influence of intraabdominal administration for 4 days of alpha 2-macroglobulin concentrate with a stabilizer, healing of the burn wounds, normalization of a state of the animals occurred 2 times more rapidly than in control ones, activity of acid proteinases restored by day 5 (in control--by day 14) due to increase in activity of proteolytic enzyme inhibitors.

