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Bone Cells and Tissue

Bone Cells and Tissue

Bones contain a relatively small number of cells entrenched in a matrix of organic and inorganic components. Although bone cells compose only a small amount of the bone volume, they are crucial to its function. Four types of cells are found within the bone tissue— osteoblasts, osteocytes, osteogenic cells, and osteoclasts.
Osteoblasts and Osteocytes
The osteoblast is the bone cell responsible for forming new bone tissue. It is found in the growing portions of bone, including the...

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Related Experiment Video

Updated: Jan 13, 2026

A Human Bone Marrow 3D Model to Investigate the Dynamics and Interactions Between Resident Cells in Physiological or Tumoral Contexts

A Human Bone Marrow 3D Model to Investigate the Dynamics and Interactions Between Resident Cells in Physiological or Tumoral Contexts

Published on: December 16, 2022

[Functional study of cultured bone cells].

F Eb, T L Nguyen, J Drouet

Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences. Serie D: Sciences Naturelles

|October 27, 1976

Summary

This summary is machine-generated.

Osseous cells in culture produce key bone components like glycosaminoglycans and collagen. Mineral salt micro-crystals form within these cells after five days of observation.

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Last Updated: Jan 13, 2026

A Human Bone Marrow 3D Model to Investigate the Dynamics and Interactions Between Resident Cells in Physiological or Tumoral Contexts

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Published on: March 8, 2014

Area of Science:

Cell Biology
Biochemistry
Histochemistry

Context:

Investigating the in vitro behavior of osseous cells.
Utilizing classical histochemical reactions and polarizing microscopy.

Purpose:

To characterize the synthesis and excretion of extracellular matrix components by osseous cells.
To identify the presence and location of mineral salt micro-crystals in cultured osseous cells.

Summary:

Osseous cells in culture were observed to synthesize and excrete glycosaminoglycans, collagen, and alkaline phosphatases.
Polarizing microscopy revealed the formation of mineral salt micro-crystals specifically within the cells and cellular groupings after five days of culture.

Impact:

Provides insight into the early stages of bone matrix formation and mineralization in vitro.
Highlights the cellular localization of mineral deposition during bone cell culture.