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The safety of antidepressants
1Department of Psychiatry, University of Amsterdam, The Netherlands.
Drugs
|January 1, 1992
Abstract:
In this article, a distinction is proposed between safe and less safe antidepressants. The safety of 18 antidepressants is discussed in relation to 3 principal issues: the safety of the drug in the event of an overdose; the seriousness of its side effects; and the existence of dangerous interactions. On the basis of present information, it can be said with reasonable confidence that fluoxetine, fluvoxamine and paroxetine are safe antidepressants, and with some reservation (mainly because of hypnosedation) the same can be said of mianserin and trazodone.