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Related Experiment Videos

Developmental selection of mutations.

L L WHYTE

    Science (New York, N.Y.)
    |October 7, 1960
    PubMed
    Summary
    This summary is machine-generated.

    Evolutionary direction can be shaped by internal genotype selection during development, not just external phenotype selection. This developmental selection possibility warrants consideration in evolutionary biology and cellular organization studies.

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    A hypothesis regarding the brain modifications underlying memory.

    Brain : a journal of neurology·1954

    Area of Science:

    • Evolutionary Biology
    • Developmental Biology
    • Cellular Organization

    Background:

    • Traditional evolutionary theory emphasizes external selection of phenotypes.
    • Internal genetic mechanisms during development are increasingly recognized as evolutionary drivers.

    Purpose of the Study:

    • To propose and support the concept of internal genotype selection influencing evolutionary trajectories.
    • To highlight the significance of developmental processes in evolutionary change.

    Main Methods:

    • Theoretical consideration of developmental pathways.
    • Review of existing biological theory and experimental evidence.

    Main Results:

    • Internal selection of genotypes during development can direct evolution.
    Keywords:
    GENETICS

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  • This contrasts with, or complements, external selection acting on phenotypes.

    • Conclusions:

    • Evolutionary biology must incorporate developmental selection mechanisms.
    • Nuclear and cellular organization research should consider these internal evolutionary forces.