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[Indications for bone marrow graft in severe hemoglobinopathies]

A Ferster1, N Azzi, W Bujan

  • 1Unité d'Hémato-Oncologie, Hôpital Universitaire des Enfants Reine Fabiola, Bruxelles.

Allogenic bone marrow transplantation (ABMT) is the only curative approach for sickle cell anemia and major beta-thalassemia. In sickle cell anemia, ABMT can be proposed for severe clinical disease. In major beta-thalassemia, it must be proposed to young patients who have an HLA identical familial donor.

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