Related Experiment Video
Updated: Aug 14, 2026

Analysis of Cell Cycle Position in Mammalian Cells
Published on: January 21, 2012
Cyclin D1 messenger RNA is inducible by platelet-derived growth factor in cultured fibroblasts
1Jefferson Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107-5541.
Abstract:
In fibroblasts in culture, the levels of cyclin D1 mRNA are growth regulated. In mouse and in human fibroblasts, both serum and platelet-derived growth factor increase cyclin D1 mRNA levels with similar kinetics of induction. Insulin-like growth factor 1 by itself does not induce cyclin D1 expression, and an antisense oligodeoxynucleotide to the insulin-like growth factor 1 receptor RNA does not affect the growth-regulated levels of cyclin D1 mRNA.
More Related Videos
09:39Drug-induced Sensitization of Adenylyl Cyclase: Assay Streamlining and Miniaturization for Small Molecule and siRNA Screening Applications
Published on: January 27, 2014
06:54Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
Published on: October 27, 2020
Related Concept Videos
Positive Regulator Molecules
Positive Regulator Molecules
Inhibition of Cdk Activity
Mitogens and the Cell Cycle
Amplifying Signals via Second Messengers
MAPK Signaling Cascades