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Cloning and functional expression of a cDNA encoding the mouse beta 2 subunit of the kainate-selective glutamate
T Morita1, K Sakimura, E Kushiya
1Department of Neuropharmacology, Faculty of Science, Niigata University, Japan.
Brain Research. Molecular Brain Research
|June 1, 1992
Abstract:
The primary structure of the mouse glutamate receptor beta 2 subunit has been deduced by cloning and sequencing cDNA. The beta 2 subunit has structural characteristics common to the subunits of glutamate-gated ion channels. Expression of the cloned cDNA in Xenopus oocytes yields functional glutamate receptor channels selective for kainate.