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Updated: Jul 23, 2026

Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma
Published on: January 9, 2019
[Application of microwaves in special and immunohistochemical staining]
1Department of Pathology, Sun Yat-sen University of Medical Sciences, Guangzhou.
Abstract:
Special and immunohistochemical staining are commonly used in clinicopathological diagnosis. However, the processing of most staining methods takes quite a long time even to 1-2 days. Application of microwaves to the staining process such as for nerve myelin, striated muscle fibers, acid mucin, melanin, hemosederin, aspergillus, basement membrane, HHF-35, desmin, cytokeratin, etc. The results were satisfactory similar to those by the ordinary methods and the time required was greatly shortened. Besides, the titres of antibody required were also similar as those used for routine immunohistochemical technique. It is assumed that application of microwaves in staining process might be valuable for pathological diagnosis and particularly the efficiency could be greatly enhanced.
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